Bioinformatics Research and Applications [electronic resource] : 10th International Symposium, ISBRA 2014, Zhangjiajie, China, June 28-30, 2014. Proceedings / edited by Mitra Basu, Yi Pan, Jianxin Wang.

Predicting Disease Risks Using Feature Selection Based on Random Forest and Support Vector Machine -- Phylogenetic Bias in the Likelihood Method Caused by Missing Data Coupled with Among-Site Rate Variation: An Analytical Approach -- An Eigen decomposition Method for Protein Structure Alignment -- Functional Interplay between Hemagglutinin and Neuraminidase of Pandemic 2009 H1N1 from the Perspective of Virus Evolution -- Predicting Protein Submitochondrial Locations Using a K-Nearest Neighbors Method Based on the Bit-Score Weighted Euclidean Distance -- Algorithms Implemented for Cancer Gene Searching and Classifications -- Dysregulated microRNA Profile in HeLa Cell Lines Induced by Lupeol -- A Simulation for Proportional Biological Operational Mu-Circuit -- Computational Prediction of Human Saliva-Secreted Proteins -- A Parallel Scheme for Three-Dimensional Reconstruction in Large-Field Electron Tomography -- An Improved Correlation Method Based on Rotation Invariant Feature for Automatic Particle Selection -- An Effective Algorithm for Peptide de novo Sequencing from Mixture MS/MS Spectra -- Identifying Spurious Interactions in the Protein-Protein Interaction Networks Using Local Similarity Preserving Embedding -- Multiple RNA Interaction with Sub-optimal Solutions -- Application of Consensus String Matching in the Diagnosis of Allelic Heterogeneity (Extended Abstract) -- Continuous Time Bayesian Networks for Gene Network Reconstruction: A Comparative Study on Time Course Data -- Drug Target Identification Based on Structural Output Controllability of Complex Networks -- NovoGMET: De Novo Peptide Sequencing Using Graphs with Multiple Edge Types (GMET) for ETD/ECD Spectra -- Duplication Cost Diameters -- Computational Identification of De-Centric Genetic Regulatory Relationships from Functional Genomic Data -- Classification of Mutations by Functional Impact Type: Gain of Function, Loss of Function and Switch of Function -- Network Analysis of Human Disease Comorbidity Patterns Based on Large-Scale Data Mining -- Identification of Essential Proteins by Using Complexes and Interaction Network -- GenoScan: Genomic Scanner for Putative miRNA Precursors -- Searching SNP Combinations Related to Evolutionary Information of Human Populations on HapMap Data -- 2D Pharmacophore Query Generation -- Structure-Based Analysis of Protein Binding Pockets Using Von Neumann Entropy -- A New Mathematical Model for Inbreeding Depression in Large Populations -- dSpliceType: A Multivariate Model for Detecting Various Types of Differential Splicing Events Using RNA-Seq -- Conformational Transitions and Principal Geodesic Analysis on the Positive Semidefinite Matrix Manifold -- Joint Analysis of Functional and Phylogenetic Composition for Human Microbiome Data -- schematikon: Detailed Sequence-Structure Relationships from Mining a Non-redundant Protein Structure Database (Extended Abstract) -- PNImodeler: Web Server for Inferring Protein Binding Nucleotides from Sequence Data -- A MCI Decision Support System Based on Ontology -- Context Similarity Based Feature Selection Methods for Protein Interaction Article Classification -- Network Propagation Reveals Novel Genetic Features Predicting Drug Response of Cancer Cell Lines -- Splice Site Prediction Using Support Vector Machine with Markov Model and Codon Information -- Exploiting Topic Modeling to Boost Metagenomic Sequences Binning -- Network-Based Method for Identifying Overlapping Mutated Driver Pathways in Cancer -- Completing a Bacterial Genome with in silico and Wet Lab Approaches -- Protein Function Prediction: A Global Prediction Method with Multiple Data Sources -- A microRNA-Gene Network in Ovarian Cancer from Genome-Wide QTL Analysis -- K-Profiles Nonlinear Clustering -- Estrogen Induced RNA Polymerase II Stalling in Breast Cancer Cell Line MCF7 -- A Knowledge-Driven Approach in Constructing a Large-Scale Drug-Side Effect Relationship Knowledge Base for Computational Drug Discovery -- Systems Biology Approach to Understand Seed Composition -- Prediction of the Cooperative cis-regulatory Elements for Broadly Expressed Neuronal Genes in Caenorhabditis Elegans -- Improving the Mapping of the Smith-Waterman Sequence Database Search Algorithm onto CUDA GPUs -- VFP: A Visual Tool for Predicting Gene-Fusion Base on Analyzing Single-end RNA-Sequence -- A Novel Method for Identifying Essential Proteins from Active PPI Networks -- RAUR: Re-alignment of Unmapped Reads with Base Quality Score -- PIGS: Improved Estimates of Identity-by-Descent Probabilities by Probabilistic IBD Graph Sampling -- Clustering PPI Data through Improved Synchronization-Based Hierarchical Clustering Method -- Order Decay in Transcription Regulation in Type 1 Diabetes -- Simulated Regression Algorithm for Transcriptome Quantification.