TY - BOOK AU - Wagner,Andreas TI - Robustness and evolvability in living systems SN - 9780691134048 PY - 2005///] CY - Princeton, New Jersey PB - Princeton University Press KW - Molecular evolution KW - Mutation (Biology) KW - Biological systems KW - Stability KW - Robust Control N1 - Includes bibliographical references (pages [323]-358) and index; Introduction -- The genetic alphabet -- The genetic code -- RNA structure -- Proteins and point mutations -- Proteins and recombination -- Regulatory DNA regions and their reorganization in evolution -- Metabolic pathways -- Metabolic networks -- Drosophila segmentation and other gene regulatory networks -- Phenotypic traits, cryptic variation, and human diseases -- The many ways of building the same body -- Neutral spaces -- Evolvability and neutral mutations -- Redundancy of parts or distributed robustness? -- Robustness as an evolved adaptation to mutations -- Robustness as an evolved adapatation to environmental change and noise -- Robustness and fragility: advantages to variation and trade-offs -- Robustness in natural systems and self-organization -- Robustness in man-made systems UR - http://site.ebrary.com/lib/nationallibgovin/Doc?id=10782425 ER -